NAD+ is the essential coenzyme that powers every cell in your body. As levels decline with age, energy, focus, and vitality suffer. SubQ NAD+ therapy restores optimal cellular function — from see pricingnth.
Start Your NAD+ Protocol →Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in every living cell, playing a central role in energy metabolism, DNA repair, and cellular aging. NAD+ is essential for the function of mitochondria — the "power plants" of cells — converting nutrients into ATP, the energy currency of the body. It also activates sirtuins, a class of proteins associated with longevity and cellular stress response.
NAD+ levels decline significantly with age — by midlife, most adults have roughly half the NAD+ they had in their 20s. This decline correlates with reduced energy, cognitive decline, impaired DNA repair, and accelerated aging. Research led by David Sinclair at Harvard and others has demonstrated that restoring NAD+ levels in aging animals reverses many markers of aging, with compelling human data emerging across energy, cognition, and metabolic health.
At PeptidesRx, we prescribe NAD+ as an RTU (ready-to-use) subcutaneous formulation. Unlike IV NAD+ infusions that require 4–8 hours in a clinic, SubQ NAD+ is self-injected at home 3x per week — delivering consistent, effective results with the convenience of at-home therapy. All NAD+ is compounded by licensed U.S. pharmacies under pharmaceutical-grade quality standards.
NAD+ is the essential electron carrier in the cellular respiration chain, enabling mitochondria to efficiently convert food into ATP energy — the fuel for every cellular process.
Activates PARP enzymes responsible for DNA repair, helping cells fix damage accumulated from aging, UV exposure, and metabolic stress — slowing age-related decline.
Fuels sirtuin proteins (SIRT1–SIRT7) — longevity-associated enzymes that regulate inflammation, metabolism, circadian rhythm, and cellular stress response.
Supports neuronal health, reduces neuroinflammation, and improves cognitive function — reducing brain fog, improving focus, and protecting against neurodegenerative decline.
NAD+ addresses aging and energy depletion at the cellular level — the root cause of fatigue, brain fog, and metabolic decline.
NAD+ therapy is ideal for adults experiencing chronic fatigue, brain fog, cognitive decline, or a general sense of "slowing down" — particularly from the mid-30s onward when NAD+ levels begin declining significantly. It's also highly valued by high performers seeking cognitive optimization, executives and athletes who need sustained mental and physical energy, and individuals focused on healthy aging and longevity.
NAD+ is an excellent standalone protocol and an exceptional stack partner. It pairs powerfully with Sermorelin (the NAD+ + Sermorelin stack addresses energy, sleep, GH, and cognitive function comprehensively), with semaglutide during weight loss (supporting cellular energy during caloric restriction), and with testosterone replacement for complete men's optimization.
NAD+ therapy is generally well-tolerated across age groups. Individuals with active cancer are advised to consult with their oncologist before beginning NAD+ therapy, as NAD+ fuels cellular energy which could theoretically support cancer cell metabolism. Our providers will review your health history and confirm appropriateness.
SubQ NAD+ is administered 3x per week for consistent cellular replenishment — no IV clinic required.
| Parameter | Details |
|---|---|
| Standard Dose (500mg vial) | 50–100mg SubQ, 3x per week |
| Higher Dose (1,000mg vial) | 100–200mg SubQ, 3x per week |
| Timing | Morning preferred (energy boost throughout day) |
| Formulation | RTU (Ready-To-Use) — no mixing required |
* SubQ injection into belly or thigh. RTU formulation is pre-mixed and ready to inject. No reconstitution needed.
Many patients report improved energy and reduced fatigue within the first week. Some notice improved clarity and mood immediately after early doses.
Brain fog notably reduces. Focus, concentration, and mental stamina improve. Energy levels are more consistent throughout the day without afternoon crashes.
Comprehensive improvements in energy, cognition, sleep quality, and metabolic efficiency. Many patients report feeling "years younger" in terms of vitality and mental sharpness.
Consistent NAD+ therapy supports sirtuin activity, DNA repair, and cellular health over time — contributing to healthier aging and reduced risk of age-related metabolic decline.
No hidden fees. Consultation, prescription, and medication included.