The most powerful cognitive + anxiolytic peptide combination available. Semax boosts BDNF/NGF for sharper thinking and neuroplasticity. Selank modulates GABA and lowers cortisol for calm focus without sedation. Together they deliver the mental performance and stress resilience you've been looking for. Convenient nasal spray form. Prescribed online for $304.
Get Semax + Selank Prescribed →Semax and Selank are Russian-developed neuropeptides that work through complementary mechanisms — one sharpening the mind, one calming the nervous system.
Semax is a synthetic heptapeptide analog of ACTH (adrenocorticotropic hormone) developed in Russia and used clinically for neurological conditions. Its primary action is the upregulation of BDNF (Brain-Derived Neurotrophic Factor) and NGF (Nerve Growth Factor) — the two most critical proteins for neuroplasticity, neuron survival, and cognitive performance. By promoting BDNF and NGF expression, Semax enhances synaptic formation, memory consolidation, learning capacity, and long-term neuroprotection. It also modulates dopamine and serotonin pathways for improved mood and motivation.
Selank is a synthetic heptapeptide derived from tuftsin (an immunomodulatory peptide) with powerful anxiolytic properties. Unlike benzodiazepines, Selank reduces anxiety through GABAergic modulation without causing sedation, dependence, or cognitive impairment. It also reduces cortisol and regulates serotonin metabolism, creating a state of relaxed alertness rather than sedated calm. Selank has been used clinically in Russia for anxiety disorders, stress, and PTSD — and research shows it has additional neuroprotective and immunomodulatory effects.
Semax dramatically increases BDNF and NGF — the brain's growth factors. This promotes new synaptic connections, enhances memory encoding, and supports long-term neuroprotection.
Selank modulates GABA receptors to reduce anxiety without sedation or dependence. Unlike benzodiazepines, it doesn't impair cognition — it enhances it while eliminating anxious interference.
Selank reduces cortisol levels and normalizes stress hormone responses — lowering baseline stress reactivity and improving resilience to cognitive and psychological stress.
Both peptides modulate monoamine neurotransmitters — dopamine for motivation and focus, serotonin for mood stability. Together they create neurochemical balance without artificial stimulation.
Semax + Selank nasal spray is easy to use — no injections, no reconstitution. Simply spray and go.
| Protocol | Dose | Frequency |
|---|---|---|
| Standard Protocol | 2 sprays per nostril | 2–3x daily |
| Concentration | 2.5mg/2.5mg per mL | 15mL total (~3 months) |
| Storage | Refrigerate when not in use | Good for 6 months refrigerated |
* Nasal spray provides excellent bioavailability through the olfactory pathway with direct CNS access — more convenient than injection with comparable efficacy for most users. Protocol set by your licensed provider.
Also available stacked with NAD+ or Methylene Blue for enhanced cognitive protocols. View full catalog →